We review the scope and limits of theoretical accounts of musical prediction with respect to feature-based and temporal prediction. While the concept of prediction is unproblematic for basic single-stream features such as melody, it is not straight-forward for polyphonic structures or higher-order features such as formal predictions. Behavioural results based on explicit and implicit (priming) paradigms provide evidence of priming in various domains that may reflect predictive behaviour. Computational learning models, including symbolic (fragment-based), probabilistic/graphical, or connectionist approaches, provide well-specified Smoothened Agonist predictive

models of specific features and feature combinations. While models match some experimental results, full-fledged music prediction cannot yet be modelled. Neuroscientific results regarding the early right-anterior negativity

(ERAN) and mismatch negativity (MMN) reflect expectancy violations on different levels of processing complexity, and provide some neural evidence for different predictive mechanisms. At present, the combinations of neural and computational modelling methodologies are at early stages and require further research. (C) 2012 Elsevier B.V. All rights reserved.”
“Recent advances in functional brain imaging offer unique opportunities to explore the neurofunctional basis ACY-738 of tools used to assess personality differences which have proven their clinical usefulness. In this functional magnetic resonance imaging (fMRI) study, Bcl-2 pathway the focus was on the amygdala

activation and we investigated whether individual differences in activity of the amygdala following presentation of emotional expressions in the face and the whole body may be systematically related to the presence of Type D (distressed) personality or to its constituting factors, Negative Affectivity (NA) and Social Inhibition (SI). Our results show that the observed difference in amygdala activity between fearful and neutral expressions was present in participants that did not meet the criteria for Type D personality, while this effect was absent in participants that could be classified as Type D personality. Our correlation analyses further showed that the activation in the left amygdala elicited by fearful, versus neutral bodily expressions correlated negatively with the Negative Affectivity score. The same pattern was observed for the right amygdala for fearful facial and bodily expressions when contrasted with neutral facial and bodily expressions. (C) 2008 Elsevier Masson SAS. All rights reserved.”
“Objective:\n\nDenture adhesives have long been recognised by denture wearers as a useful adjunct to denture retention and stability.