Smoking topography data were not collected. Immediately after participants extinguished the cigarette, they completed post-cigarette assessments identical to the pre-cigarette assessments except for the inclusion of an additional Cigarette Evaluation www.selleckchem.com/products/PF-2341066.html Questionnaire (CEQ; see Experimental Session Measures section). As previously reported, subjective measures during the ad lib smoking of a single cigarette following normal smoking have high reliability (Perkins et al., 2012). Baseline Session Measures Structured Clinical Interview for DSM-IV NonPatient Edition The Structured Clinical Interview for DSM-IV was used to assess psychiatric diagnoses for eligibility purposes (First, Spitzer, Gibbon, & Williams, 2002).

Fagerstr?m Test of Nicotine Dependence The Fagerstr?m Test of Nicotine Dependence (FTND) is a well-validated six-item measure of nicotine-dependence severity (Heatherton, Kozlowski, Frecker, & Fagerstr?m, 1991). Smoking History Questionnaire An author-constructed smoking history questionnaire was used to assess basic information including number of cigarettes smoked per day, age of smoking onset, and other relevant smoking characteristics. The Anxiety Sensitivity Index The Anxiety Sensitivity Index (ASI; Reiss et al., 1986) is a 16-item questionnaire measuring the extent to which one fears the potential negative consequences of anxiety-related symptoms and sensations (e.g., ��It scares me when I feel shaky��). Items were rated on a 5-point Likert scale ranging from 0 (very little) to 4 (very much), and a total score was computed.

The ASI has three lower order factors (physical, psychological, and social concerns) that all load on a single common global factor (Zinbarg, Barlow, & Brown, 1997). Here, we utilized the total ASI score because: (a) it represents the global AS factor and thus incorporates general sensitivity to a variety of anxiety-causing situations that may each influence smoking; and (b) we wished to reduce the number of statistical tests performed and corresponding type-I error rates. The ASI total scale has been shown to possess good psychometric properties and exhibits excellent discriminant validity from trait anxiety and other constructs (McNally, 2002; Peterson & Heilbronner, 1987; Zvolensky, Kotov, Antipova, & Schmidt, 2005). The internal consistency of the ASI in this sample was good (Cronbach��s �� = .85).

The Mood and Anxiety Symptom Questionnaire��Short Form Anxious Arousal Subscale The Mood and Anxiety Symptom Batimastat Questionnaire (MASQ; Watson et al., 1995) is a self-report measure of affective symptoms in the past week. Participants indicate how much they have experienced each symptom on a 5-point Likert-type scale (1 = not at all to 5 = extremely). Only the 17-item Anxious Arousal subscale (MASQ-AA) was used in this report as it addresses symptoms of somatic tension and arousal (e.g.