In this placebo-controlled

study, it was demonstrated that vardenafil can improve continence recovery after nerve-sparing surgery. The daily use of vardenafil seems to provide better continence rates, GDC-0449 research buy although it does not seem to influence the time needed to achieve full continence. This year’s 24th annual EAU Congress in Stockholm presented a great opportunity for urologists to present their newest data on contemporary issues. The information and the results presented were very promising. Inhibitors,research,lifescience,medical Barcelona is host to the 25th annual EAU Congress from April 16 to 20, 2010.
Urinary incontinence (UI) affects substantial proportions of men1; the estimated prevalence of UI varied from 11% among those aged 60 to 64 years to 31% in older men, and from 16% among white men to 21% among African American men.2 Daily UI was reported by 30% to 47% and weekly UI by 15% to 37% of community-dwelling men.2 A small proportion (22%) of men with weekly UI episodes ever sought Inhibitors,research,lifescience,medical medical care for this problem, whereas 40% of treated men reported moderate to great frustration with continued urine leakage.3 Baseline mechanisms of UI include overactive bladder that may result in urge UI and poor urethral sphincter function that can result in primary urethral incompetence and stress UI.4,5 Baseline mechanisms of incontinence lead to variable definitions,

risk factors, Inhibitors,research,lifescience,medical and Inhibitors,research,lifescience,medical effective interventions to prevent and treat UI.5 This review was commissioned as background material for a National Institutes of Health Office of Medical Applications of Research State of the Science Conference on Incontinence. We aimed to synthesize evidence of the effectiveness of different clinical interventions to prevent the occurrence and progression of UI in community-dwelling Inhibitors,research,lifescience,medical men. Methods Literature Search Strategy and Eligibility Criteria

Studies were sought from a wide variety of sources, including MEDLINE via PubMed, the Cumulative Index to Nursing and Allied Health Literature, Cochrane databases, and manual searches of reference lists from systematic reviews. Search strategies are described in the full-text report, available at http://www.ahrq.gov/downloads/pub/evidence/pdf/fuiad/fuiad.pdf. next Three investigators independently decided on the eligibility of the studies.6 Full texts of the original epidemiologic studies published in English after 1989 were examined to include studies with eligible outcomes, defined as prevalence and incidence of incontinence, absolute and adjusted relative risk (RR) of incidence, and progression of urinary incontinence in community-dwelling men. We included randomized, controlled trials (RCTs) of clinical interventions on incontinence. We excluded studies with children and adolescents, studies with no information relevant to incidence and progression of incontinence, and case series with fewer than 100 men and no control.