This study characte-rized the chemical components of Zhachong Shisanwei Pills rapidly the very first time, laying a foundation for additional study in the pharmacodynamic material basis and quality evaluation.This study is designed to acetylate Rehmannia glutinosa polysaccharides by acetic anhydride strategy, optimize procedure parameters and examine their particular anti-oxidant task. Utilizing the level of substitution(D_s) as a criterion, the effects of reaction time, acetic anhydride-to-polysaccharides ratio and temperature were investigated. Process variables had been optimized by single-factor experiment and response surface methodology. The infrared spectroscopy(IR) and scanning electron microscopy(SEM) proved the effective acetylation and were utilized to preliminarily evaluate the structural qualities of acetylated types. The outcome indicated that the D_s ended up being 0.327 under the ideal technological conditions, including m(acetic anhydride)m(R. glutinosa polysaccharides)=2.70, reaction time 3.0 h and temperature 48 ℃. More Primary immune deficiency , the anti-oxidant properties of acetylated derivatives were investigated in vitro and acetylation was discovered efficient to improve the antioxidant task of R. glutinosa polysaccharides. This study provides a reference for the further development and application of R. glutinosa polysaccharides.There are 200-500 types of Potentilla(Rosaceae) worldwide, among which 90 species tend to be widely distributed in Asia and have a lengthy history of ethnic medicinal usage. In accordance with our data, an overall total of 367 compounds are separated and identified from plants for this genus, including terpenoids, flavonoids, phenolic acids, tannins, and phenylpropanoids. The medicinal materials created from these plants mainly have actually antioxidative, bloodstream sugar-lowering, anti inflammatory, anti-tumor, aerobic system-protecting, neuroprotective, and hepatoprotective activities. This study systematically Apatinib purchase ratings the investigation development on substance constituents and pharmacological tasks of Potentilla flowers to provide a basis for further study and clinical application.This study systematically sorted out of the existing researches about Tianshu Capsules in the treatment of migraine(syndrome of blood stasis blocking collaterals, syndrome of ascendant hyperactivity of liver Yang), and conducted comprehensive clinical analysis through "6+1" dimensions of security, effectiveness, economy, innovation, suitability, accessibility, and faculties of conventional Chinese medicine(TCM) to embody the advantages and qualities and make clear the complete clinical position of Tianshu Capsules. The value of each dimension had been computed via wellness technology evaluation, the multi-criteria decision analysis(MCDA) mo-del and CSC v2.0 software. The results were graded into four amounts of A, B, C, or D from high to reasonable. In line with the readily available researches, Tianshu Capsules had reduced and controllable dangers, using the safety rated as A. The drug has actually apparent clinical significance into the treatment of migraine(syndrome of bloodstream stasis blocking collaterals, problem of ascendant hyperactivitules within the treatment of migraine(syndrome of blood stasis preventing collaterals and syndrome of ascendant hyperactivity of liver Yang) is class A. According to the Comprehensive medical Evaluation Management tips of Drugs(trial variation 2021) issued by the nationwide Health Commission associated with People’s Republic of China, we advice that Tianshu Capsules dealing with migraine is transformed Nasal pathologies into relevant policy outcomes for clinical medicine management based on procedures.This medical value-oriented comprehensive analysis of drugs was performed according to Guidelines for Management of Comprehensive Clinical Evaluation of Drugs(trial variation 2021), because of the qualitative and quantitative analysis practices adopted. On the basis of the evidence-based medicine, epidemiology, clinical medication, pharmacoeconomics, mathematical data, and wellness technology evaluation(HTA), the clinical worth of Ginkgolide Injection ended up being evaluated through the "6+1" measurement by providing body weight to the criterion degree and list degree and computing with multi-criteria decision analysis(MCDA) design and CSC v2.0. After entering the market, Ginkgolide Injection has been subjected to phase Ⅳ medical trial, spontaneous reporting system(SRS)-based data tracking, organized review and Meta-analysis, intense poisoning and long-term poisoning assays, active tracking, and RCTs, and the proof safety had been sufficient. The outcomes of active tracking revealed that the occurrence of negative reactionsB. This medicine belonged to Chinese medicinal shot. The large-sample real-world study revealed rich individual usage knowledge, so it had been grade C for the traditional Chinese medication feature. Based on the extensive analysis, the medical value of Ginkgolide Injection in the treatment of cerebral infarction dropped into course A. it’s advocated that it could be transformed into the appropriate policy link between fundamental medical medicine administration based on the process.Based on Guidelines for the handling of medical Comprehensive Evaluation of Drugs(trial variation 2021), this study is designed to straighten out the clinical proof of Huangkui Capsules(HC) into the remedy for persistent kidney conditions in facets of protection, effectiveness, economy, development, suitability, accessibility, and faculties of standard Chinese medicine( "6+1" dimensions) from real-world data, secondary literature evaluations, surveys, and community data, with all the methods in evidence-based medication, epidemiology, pharmacoeconomics, and health technology. Furthermore, with multi-criteria decision analysis(MCDA) design and CSC v2.0, the clinical value of the medication is comprehensively considered.