(C) 2012 Elsevier B.V. All rights reserved.”
“We compared cure rates of tension-free vaginal tape (TVT) with intravaginal SIS3 price slingplasty (IVS) and evaluated changes in cure rates over time.\n\nOne hundred three underwent TVT and 213 underwent IVS. Follow-ups were done at 3 months, 1 year, and 5 years.\n\nThe following results were found: objective cure for TVT 98-95-94% vs. IVS 86-86-80% (p < 0.03); subjective cure for TVT 82-79-74% vs. IVS 79-81-71% (NS). In IVS, a significant decline in subjective cure took place. Vaginal erosions were found
in 11.8% of women in the IVS group and none in the TVT group.\n\nTVT is an effective and stable treatment, whereas IVS has a significant Selleckchem MLN4924 inferior objective cure rate, and a significant decline in subjective cure rate occurred over time. A high rate of vaginal erosions was found in the IVS group. We cannot recommend the use of multifilament polypropylene tape (IVS) for surgical treatment of stress urinary incontinence.”
“A new technique of insulin resistance assessment, using nuclear imaging, was developed. On a model of experimental myocardial infarction in rats, our results indicate a significant phenomenon of cardiac insulin resistance
seven days after ischaemia. This study demonstrates the sensitivity of the technique for measuring insulin resistance by nuclear imaging. (C) 2011 Elsevier Masson SAS. All rights reserved.”
“Plant cells utilize mobile transcription factors to transmit intercellular signals when they perceive environmental stimuli or initiate developmental programmes. Studies on these novel cell-to-cell signals have accumulated multiple pieces of evidence showing that non-cell-autonomous transcription factors play pivotal roles in most processes related to the formation and development of plant organs. Recent studies have explored this website the evolution of mobile transcription factors and proposed mechanisms for their trafficking through plasmodesmata, where a selective system exists to facilitate this process. Mobile transcription factors contribute
to the diversity of the intercellular signalling network, which is also established by peptides, hormones, and RNAs. Crosstalk between mobile transcription factors and other intercellular molecules leads to the development of complex biological signalling networks in plants. The regulation of plasmodesmata appears to have been another major step in controlling the intercellular trafficking of transcription factors based on studies of many plasmodesmal components. Furthermore, diverse omics approaches are being successfully applied to explore a large number of candidate transcription factors as mobile signals in plants. Here, we review these fascinating discoveries to integrate current knowledge of non-cell-autonomous transcription factors.