This allows for the observation of single-shot NMR signals with very high signal-to-noise ratio under conditions where conventional NMR is not possible, due to the low concentration of P-31 and the small equilibrium polarization.(C) 2011 American Institute of Physics. [doi:10.1063/1.3577614]“
“QUESTIONS UNDER STUDY: Hospitality workers are a population particularly at risk from the noxious effects of environmental tobacco
smoke (ETS). The Canton of Vaud, Switzerland banned smoking in public places in September 2009. This prospective study addresses the impact of the ban on the health of hospitality workers.
METHODS: ETS exposure was evaluated using a passive sampling device that measures airborne nicotine; lung function was assessed by spirometry; health-related quality of life, ETS exposure symptoms buy JQ1 and satisfaction were measured by questionnaire.
RESULTS: 105 participants (smokers and non-smokers) were recruited initially and 66 were followed up after one year. ETS exposure was significantly lower after the ban. Hospitality workers had lower pre-ban forced expiratory volume in one second (FEV(1)) and forced vital capacity (FVC) values than expected. FEV(1) remained stable after the ban, with a near-significant increase in the subgroup
of asthmatics only. FVC selleck chemicals llc increased at one year follow-up from 90.42% to 93.05% (p = 0.02) in the entire cohort; women, non-smokers and older participants gained the greatest benefit. The health survey showed an increase in physical wellbeing after the ban, the greatest benefit being observed in non-smokers. ETS exposure symptoms were less frequent after the ban, especially red and irritated
eyes and sneezing. The new law was judged useful and satisfactory by the vast majority of employees, including smokers.
CONCLUSION: The recent cantonal ban on smoking in public places brought about an improvement in lung function, physical well-being and ETS symptoms of hospitality workers, including smokers.”
“We report a case of a cerebral tuberculoma in a 60-year-old woman with rheumatoid NSC-23766 arthritis while receiving the anti-tumor necrosis factor alpha monoclonal antibody, adalimumab (Humira), for active disease. MR brain imaging for dyspraxia revealed a left parietal ring-enhancing lesion, which on resection was shown to be a necrotizing granuloma. There were no associated pulmonary lesions, and the patient was systemically well. Sputum and urine cultures were negative for tuberculosis. The patient was treated with anti-tuberculous medications and made an excellent recovery. We consider this to be the first documented case of tuberculosis involving the central nervous system occurring in the setting of adalimumab treatment.