Table 3 Source of infection Source of infection Patients n° (%) A

Table 3 Source of infection Source of infection Patients n° (%) Appendicitis 350 (38,4%) Cholecystitis 131 (14,4%) Post-operative 108 (11,8%) Colonic non diverticular perforation 75 (8,2%) Gastroduodenal perforations 74 (8,1%) Diverticulitis 71 (7,8%) Small bowel perforation 44 (4,8%) Bioactive Compound Library price Others 45 (4,9%) PID 7 (0,8%) Post traumatic perforation 7 (0,8%) 108 cases (11.8%) were attributable to post-operative infections. Anastomotic

leaks were the most prevalent cause of post-operative infection. SN-38 Of the patients with post-operative infections, 34.2% resulted from colo-rectal leaks, 15.7% from upper gastro-intestinal leaks, 12% from pancreatic leaks, 11.1% from biliary leaks, and 0.9% from urinary leaks. The most frequently performed Lazertinib procedure employed to address complicated appendicitis was the open appendectomy. 189 patients (54%) admitted for complicated appendicitis underwent open appendectomies: 135 patients (71.4%) for localized infection or abscesses and 54 patients (28.6%) for generalized peritonitis. A laparoscopic appendectomy was performed on 143 patients (40.8%) presenting with complicated acute appendicitis, 95 and 53 of whom underwent the procedure for localized peritonitis/abscesses and generalized peritonitis, respectively.

Open colonic resection was performed on three patients to address complicated appendicitis. In the other 15 cases of complicated appendicitis (4.3%), conservative treatment (percutaneous drainage, surgical drainage, and non-operative treatment) was performed. 2.3% of patients underwent percutaneous drainage and interval appendectomies to address appendicular abscesses. The most frequently performed procedure to address cholecystitis was the open cholecystectomy. 66 cholecystitis patients (50.4%) underwent this procedure.

A laparoscopic cholecystectomy was performed on 46 patients (35.1%). In the remaining cases, conservative treatment methods (percutaneous drainage, non-operative treatment) were alternatively employed. The Hartmann resection was the most frequently performed procedure to address complicated diverticulitis. 35 patients (49.3%) underwent Amine dehydrogenase a Hartmann resection, and of these resections, the vast majority were open procedures (91% open compared to 9% laparoscopic). 23 of these patients underwent a Hartmann resection for generalized peritonitis, while the remaining 12 underwent the same procedure for localized peritonitis or abscesses. Colo-rectal resection was performed in 16 cases (22.5%). Contrastingly, laparoscopic resection was performed on only two patients, (one patient with and one patient without protective stoma). Open resection was performed on 14 patients (five with and nine without stoma protection). The other patients received conservative treatment (percutaneous drainage, non-operative treatment, surgical drainage and stoma). Seven patients (9.9%) underwent laparoscopic drainage.

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