Another point to be taken into account for the management of the

Another point to be taken into account for the management of the patient is the comprehension of the local bifurcation disease causing the pseudo-occlusion: atherosclerotic processes usually involve longer tracts of the artery, limiting the possibilities

of surgery when the stenosis extends too distally, while a migrating thrombus is usually of smaller size and induces damage of the vessel wall only at the site of adhesion. We have already described the advantages of US in respect to CT and MR to identify carotid occlusions due to cardiac embolism [7] and, in these new cases, US could easily identify uncommon carotid “saddle” thrombi attached to the vessel wall and leaving the distal tract of the vessel

open and without wall disease. Alpelisib concentration Even without strictly click here following stroke guidelines, surgery was performed successfully in one case. The identification with high-resolution US of the embolic source on the plaque surface in case 3 indicated that surgery had to be performed as soon as possible, and not on elective bases. This small case series underline that high-resolution US, even with contrast agents, is a feasible and reliable technique, nowadays commonly diffused in clinical practice, with more and more detailed imaging quality. These better resolution pictures can be of help in reducing operator’s dependency, usually claimed as a major limit of Ribonucleotide reductase US investigations. The detection of dynamic, real-time, aspects “in motion” is a strong potentiality of this technique, to better understand vascular pathophysiology. Moreover, ultrasound can easily differentiated cardiac clots from local thrombosis on a complicated atherosclerotic plaque, with the related clinical implications. All these findings underline the role

of early ultrasound in the management of acute stroke patients. In conclusion, the achievement of his “kingdom” for the patient is linked to the availability of an expert joker, able to obtain the best results from his horse, besides … “saddle problems”. “
“Intravascular papillary endothelial hyperplasia (IPEH) is a relatively uncommon benign and non-neoplastic vascular lesion [1], [2], [3] and [4]. Firstly described by Masson in 1923, as an endothelial proliferation associated with thrombosis and fibrin deposition, leading to obliteration of the vascular lumen [1], [2], [3] and [4]. Histologically it is characterized by the presence of endothelium-lined papillary structures composed by a single layer of plump cells around a fibrin core that sometimes forms irregular anatomizing clefts, simulating an angiosarcoma [5], [6], [7] and [8]. However, the absence of cellular polymorphism, mitotic activity and necrosis represent a differential feature of IPEH [5]. The prognosis of this lesion is excellent, and recurrence is an unusual finding.

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